Can we book 2 one-way tickets instead of a round trip ticket? For example: Arrive in Las Vegas, but depart from New York?

Round trip flights are generally more economical and should be prioritized. You may fly out of different airports provided your itinerary booked in Egencia is within reasonable range of the flight you would've originally taken round trip just for the work event (<10% variance). Zendesk will not cover personal domestic travel. You should alert your approver of your desired travel itinerary. If you have an unusual case you would like the travel team to review, please open a ticket here.